Charles Y F Young Selected Research

Topoisomerase II Inhibitors

8/2013

Induction of DNA damage and ATF3 by retigeric acid B, a novel topoisomerase II inhibitor, promotes apoptosis in prostate cancer cells.

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Charles Y F Young Research Topics

Disease

43	Prostatic Neoplasms (Prostate Cancer) 01/2016 - 01/2002
15	Neoplasms (Cancer) 05/2018 - 03/2002
4	Neoplasm Metastasis (Metastasis) 05/2018 - 06/2010
3	Carcinogenesis 10/2013 - 01/2010
3	Carcinoma (Carcinomatosis) 01/2009 - 03/2003
3	Adenocarcinoma 07/2005 - 07/2003
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 04/2014
1	Prostatic Intraepithelial Neoplasia 07/2005
1	Bullous Pemphigoid (Pemphigoid) 07/2003
1	Fatigue 03/2003
1	Abdominal Pain (Pain, Abdominal) 03/2003
1	Vomiting 03/2003

Drug/Important Bio-Agent (IBA)

18	Androgen Receptors (Androgen Receptor)IBA 01/2016 - 07/2003
10	AndrogensIBA 01/2012 - 01/2003
7	Proteins (Proteins, Gene)FDA Link 05/2018 - 07/2003
5	Prostate-Specific Antigen (Semenogelase)IBA 05/2014 - 01/2003
5	Biomarkers (Surrogate Marker)IBA 05/2012 - 01/2003
4	retigeric acid BIBA 09/2013 - 12/2010
4	Messenger RNA (mRNA)IBA 03/2009 - 03/2002
3	Interleukin-6 (Interleukin 6)IBA 07/2014 - 05/2007
3	phenethyl isothiocyanate (PEITC)IBA 10/2013 - 01/2009
3	DNA (Deoxyribonucleic Acid)IBA 05/2012 - 01/2005
3	QuercetinIBA 06/2010 - 09/2004
2	riccardin DIBA 01/2016 - 01/2013
2	AcidsIBA 09/2013 - 01/2012
2	MicroRNAs (MicroRNA)IBA 10/2012 - 06/2010
2	OligonucleotidesIBA 09/2011 - 07/2003
2	Peptides (Polypeptides)IBA 03/2011 - 09/2007
2	SaposinsIBA 03/2011 - 09/2007
2	Vitamin D FDA LinkGeneric 01/2011 - 03/2010
2	Antineoplastic Agents (Antineoplastics)IBA 12/2010 - 03/2003
2	Ascorbic Acid (Vitamin C)FDA LinkGeneric 03/2010 - 07/2003
2	AntioxidantsIBA 03/2010 - 01/2010
2	Indicators and Reagents (Reagents)IBA 01/2008 - 05/2004
2	methylselenic acidIBA 05/2007 - 05/2004
1	Protein Disulfide-IsomerasesIBA 05/2018
1	ThioredoxinsIBA 05/2018
1	riccardin CIBA 01/2016
1	Proteasome InhibitorsIBA 01/2016
1	marchantin MIBA 01/2016
1	Docetaxel (Taxotere)FDA Link 07/2014
1	Focal Adhesion Protein-Tyrosine KinasesIBA 05/2014
1	CalreticulinIBA 05/2014
1	nimbolideIBA 05/2014
1	28-deoxonimbolideIBA 05/2014
1	IntegrinsIBA 05/2014
1	Dihydrotestosterone (Androstanolone)IBA 05/2014
1	Small Interfering RNA (siRNA)IBA 04/2014
1	NF-kappa B (NF-kB)IBA 04/2014
1	Matrix Metalloproteinases (MMPs)IBA 04/2014
1	E2F1 Transcription FactorIBA 04/2014
1	GlucosinolatesIBA 10/2013
1	trioctyl phosphine oxide (TOPO)IBA 08/2013
1	Topoisomerase II InhibitorsIBA 08/2013
1	A-Form DNA (A-DNA)IBA 01/2013
1	member 2 group B nuclear receptor subfamily 0 (small heterodimer partner protein)IBA 10/2012
1	Ethanol (Ethyl Alcohol)IBA 09/2011
1	Paclitaxel (Taxol)FDA LinkGeneric 08/2011
1	SesquiterpenesIBA 03/2011
1	myrrh resin (myrrh)IBA 03/2011
1	Calcitriol Receptors (Calcitriol Receptor)IBA 01/2011
1	EnzymesIBA 01/2011
1	RetinoidsIBA 03/2010
1	Transcription Factors (Transcription Factor)IBA 03/2010
1	Vitamin A (Retinol)FDA LinkGeneric 03/2010
1	Vitamin B Complex (B Vitamins)IBA 03/2010
1	Vitamin E FDA LinkGeneric 03/2010
1	VitaminsIBA 03/2010
1	LipidsIBA 01/2010
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2010
1	retinoic acid receptor betaIBA 11/2009
1	Microfilament Proteins (Actin Binding Proteins)IBA 03/2009
1	TubulinIBA 01/2009
1	Oxygen (Dioxygen)IBA 01/2009
1	acetyl-11-ketoboswellic acidIBA 06/2008
1	Cyclin D1IBA 06/2008
1	Immunoglobulin G (IgG)IBA 01/2008
1	Carrier Proteins (Binding Protein)IBA 01/2008
1	Sodium SeleniteIBA 05/2007
1	Mastic ResinIBA 06/2006
1	perillyl alcoholIBA 05/2006
1	Monoterpenes (Monoterpenoids)IBA 05/2006
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 02/2006
1	Sp1 Transcription FactorIBA 04/2005
1	PolyphenolsIBA 09/2004
1	SeleniumIBA 05/2004
1	methaneselenolIBA 05/2004
1	nimesulide (Aulin)IBA 08/2003
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 08/2003
1	Celecoxib (Celebrex)FDA Link 08/2003
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 08/2003
1	AntigensIBA 07/2003
1	Decitabine FDA Link 07/2003
1	beta-microseminoproteinIBA 07/2003
1	TeaIBA 03/2003

Therapy/Procedure

4	Therapeutics 09/2011 - 03/2003
3	Chemoprevention 11/2007 - 08/2003
1	Castration 07/2014
1	Oral Administration 05/2014
1	Prostatectomy (Retropubic Prostatectomy) 07/2005